Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12218396 | 0.86 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL2225494 | 0.80 | IDO1 (0.50) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL30795121 | 0.80 | IDO1 (0.50) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL12517496 | 0.76 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL2222573 | 0.73 | RAB9A (0.48) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL1073464 | 0.72 | SMN1; SMN2 (0.65) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL14503277 | 0.72 | EPHX2 (0.67) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL2279802 | 0.72 | P2RX7 (0.56) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL13023029 | 0.71 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL1548135 | 0.71 | SPHK2 (0.57) | SMN1; SMN2KMT2AMEN1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011087758-A1 | ADAMANTYL AMIDE DERIVATIVES AND USES OF SAME | H. LUNDBECK A/S (DK) | 2011-07-21 | — | — | WO | disclosed |