Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786512 | 1.00 | KMT2A (0.48) | KMT2ARAB9AUSP2SMN1; SMN2MAPK1 | |
| SCHEMBL1789011 | 0.86 | TRPV1 (0.41) | KMT2AUSP2SMN1; SMN2AKR1B1LMNA | |
| SCHEMBL30796852 | 0.86 | TRPV1 (0.41) | KMT2AUSP2SMN1; SMN2AKR1B1LMNA | |
| SCHEMBL30814194 | 0.85 | NLRP3 (0.41) | USP2SMN1; SMN2AKR1B1LMNAHTT | |
| SCHEMBL1791204 | 0.85 | NLRP3 (0.41) | USP2SMN1; SMN2AKR1B1LMNAHTT | |
| SCHEMBL30795119 | 0.85 | RAB9A (0.50) | KMT2ARAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL1789436 | 0.85 | RAB9A (0.50) | KMT2ARAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL30796353 | 0.84 | MAPT (0.50) | KMT2ARAB9AUSP2SMN1; SMN2AKR1B1 | |
| SCHEMBL30796507 | 0.84 | TRPV1 (0.42) | KMT2AUSP2SMN1; SMN2AKR1B1LMNA | |
| SCHEMBL1790031 | 0.84 | TRPV1 (0.42) | KMT2AUSP2SMN1; SMN2AKR1B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| EP-4580679-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | Biohaven Therapeutics Ltd. (VG) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |