Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 12/20 | 0.37 |
| ▸ | BRAF | P15056 | 12/20 | 0.37 |
| ▸ | NAPEPLD | Q6IQ20 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2131352 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL2131003 | 0.87 | NAPEPLD (0.46) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL2128118 | 0.85 | RAB9A (0.40) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL2129762 | 0.84 | NAPEPLD (0.39) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL30795161 | 0.84 | NAPEPLD (0.39) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL2134391 | 0.84 | RAB9A (0.43) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL30795728 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL2130853 | 0.84 | KDM4E (0.38) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL2129940 | 0.83 | GBA1 (0.37) | KDM4EALDH1A1CYP1A2GAAHPGD | |
| SCHEMBL2128433 | 0.83 | MEN1 (0.43) | KDM4EALDH1A1CYP1A2GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| EP-4580679-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | Biohaven Therapeutics Ltd. (VG) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024054807-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND TDP-43 MODULATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |