Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 3/20 | 0.50 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30796848 | 0.86 | ACHE (0.53) | PRMT5GPR119ACHESMN1; SMN2NPC1 | |
| SCHEMBL30796240 | 0.85 | GRM5 (0.47) | GPR119ACHE | |
| SCHEMBL30796727 | 0.84 | SMN1; SMN2 (0.48) | PRMT5SMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL29943772 | 0.83 | ACHE (0.46) | GPR119ACHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL28810491 | 0.83 | ACHE (0.46) | GPR119ACHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30796983 | 0.80 | GPR119 (0.56) | GPR119ACHESMN1; SMN2NPC1RAB9A | |
| SCHEMBL30796908 | 0.80 | GPR119 (0.46) | PRMT5GPR119ACHE | |
| SCHEMBL25230803 | 0.78 | SMN1; SMN2 (0.58) | GPR119SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL30408655 | 0.77 | SMN1; SMN2 (0.53) | GPR119SMN1; SMN2NPC1RAB9AGRIN2B | |
| SCHEMBL17112637 | 0.76 | SMN1; SMN2 (0.60) | GPR119SMN1; SMN2NPC1RAB9AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4539849-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244764-A1 | COMPOUNDS FOR THE TARGETED DEGRADATION OF SMARCA2 | C4 THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |