Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CDA | P32320 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17138583 | 0.78 | KDM4E (0.39) | KDM4EALDH1A1KMT2ACDAOPRM1 | |
| SCHEMBL9202125 | 0.74 | KDM4E (0.39) | KDM4EALDH1A1KMT2AOPRM1 | |
| SCHEMBL14244119 | 0.73 | — | — | |
| SCHEMBL3093245 | 0.72 | PDE7A (0.41) | KDM4EALDH1A1KMT2AOPRM1 | |
| SCHEMBL17977060 | 0.72 | NPSR1 (0.33) | ALDH1A1KMT2AL3MBTL1 | |
| SCHEMBL7358166 | 0.69 | HSD11B1 (0.39) | KDM4EALDH1A1 | |
| SCHEMBL19770247 | 0.68 | SCN9A (0.37) | KDM4EALDH1A1KMT2AOPRM1 | |
| SCHEMBL19770249 | 0.68 | SCN9A (0.37) | KDM4EALDH1A1KMT2AOPRM1 | |
| SCHEMBL726957 | 0.68 | HTR2C (0.40) | KDM4EALDH1A1HTR2CKMT2A | |
| SCHEMBL17138754 | 0.68 | CDA (0.42) | KDM4EALDH1A1HTR2CKMT2ACDA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |