Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797406 | 0.82 | KDM1A (0.44) | ALDH1A1THRBMAPTFFAR1 | |
| SCHEMBL20870178 | 0.82 | ALDH1A1 (0.47) | ACACBL3MBTL1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL5861604 | 0.81 | HTT (0.53) | L3MBTL1ALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL5861593 | 0.81 | HTT (0.53) | L3MBTL1ALDH1A1SMN1; SMN2MAPTMAPK1 | |
| SCHEMBL22868105 | 0.78 | CA12 (0.46) | L3MBTL1ALDH1A1SMN1; SMN2TP53HSP90AA1 | |
| SCHEMBL5861572 | 0.78 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1SMN1; SMN2TP53HSP90AA1 | |
| SCHEMBL2705958 | 0.78 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1SMN1; SMN2TP53HSP90AA1 | |
| SCHEMBL4124188 | 0.78 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1SMN1; SMN2TP53HSP90AA1 | |
| SCHEMBL5860319 | 0.77 | MEN1 (0.47) | L3MBTL1ALDH1A1SMN1; SMN2TP53HSP90AA1 | |
| SCHEMBL5860329 | 0.77 | MEN1 (0.47) | L3MBTL1ALDH1A1SMN1; SMN2TP53HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |