Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22868105 | 0.78 | CA12 (0.46) | SMN1; SMN2TSHRMAPTNPC1RAB9A | |
| SCHEMBL12697232 | 0.78 | TP53 (0.61) | NPSR1SORT1KCNQ3KCNQ2SMN1; SMN2 | |
| SCHEMBL2703752 | 0.77 | CA12 (0.44) | SMN1; SMN2TSHRMAPTMAPK1LMNA | |
| SCHEMBL2705958 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2TSHRMAPTMAPK1NPC1 | |
| SCHEMBL4124188 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2TSHRMAPTMAPK1NPC1 | |
| SCHEMBL5861572 | 0.74 | ALDH1A1 (0.50) | SMN1; SMN2TSHRMAPTMAPK1NPC1 | |
| SCHEMBL15223665 | 0.74 | NPSR1 (0.41) | NPSR1SORT1KCNQ3KCNQ2SMN1; SMN2 | |
| SCHEMBL12697206 | 0.74 | TDP1 (0.43) | NPSR1SORT1KCNQ3KCNQ2SMN1; SMN2 | |
| SCHEMBL6257260 | 0.73 | HIF1A (0.44) | SMN1; SMN2TSHRMAPTMAPK1NPC1 | |
| SCHEMBL5860329 | 0.73 | MEN1 (0.47) | NPSR1SMN1; SMN2TSHRMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |