Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 4/20 | 0.49 |
| ▸ | IKZF2 | Q9UKS7 | 14/20 | 0.48 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.47 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.44 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30797121 | 0.89 | CRBN (0.49) | CRBNIKZF2IKZF1CSNK1A1 | |
| SCHEMBL24572309 | 0.89 | IKZF2 (0.57) | CRBNIKZF2IKZF1DDB1 | |
| SCHEMBL30797139 | 0.85 | CRBN (0.57) | CRBNIKZF2IKZF1 | |
| SCHEMBL31736792 | 0.85 | IKZF2 (0.59) | CRBNIKZF2IKZF1DDB1 | |
| SCHEMBL31737024 | 0.85 | IKZF2 (0.59) | CRBNIKZF2IKZF1DDB1 | |
| SCHEMBL31025879 | 0.85 | IKZF2 (0.59) | CRBNIKZF2IKZF1DDB1 | |
| SCHEMBL31736849 | 0.85 | IKZF2 (0.59) | CRBNIKZF2IKZF1DDB1 | |
| SCHEMBL31736513 | 0.85 | IKZF2 (0.59) | CRBNIKZF2IKZF1DDB1 | |
| SCHEMBL30797138 | 0.84 | CRBN (0.60) | CRBNIKZF2IKZF1 | |
| SCHEMBL30797297 | 0.84 | CRBN (0.62) | CRBNIKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244817-A1 | SUBSTITUTED PIPERIDINES AS CK1A DEGRADERS | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |