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Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30797992

N#Cc1ccc(COc2cccc(-n3cc4c(c3)CNC4)n2)nc1.O=C(O)C(F)(F)F.O=C(O)C(F)(F)F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 13/20 0.34
▸ DPP4 P27487 1/20 0.33
▸ DPP8 Q6V1X1 1/20 0.33
▸ DPP9 Q86TI2 1/20 0.33
▸ DPP7 Q9UHL4 1/20 0.33
▸ GRM5 P41594 1/20 0.32
▸ ALOX5 P09917 1/20 0.32
▸ ALOX5AP P20292 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL30798276 0.88 JAK2 (0.36) GLP1RDPP4DPP8DPP9DPP7
Trifluoroacetic Acid SCHEMBL30798007 0.86 GRM2 (0.35) GLP1RGRM5
Trifluoroacetic Acid SCHEMBL30798182 0.84 GLP1R (0.46) GLP1R
SCHEMBL30798020 0.78 GRM5 (0.35) GLP1RGRM5
Trifluoroacetic Acid SCHEMBL30138407 0.76 HTR2C (0.46) DPP4DPP8DPP9DPP7
Trifluoroacetic Acid SCHEMBL30797976 0.74 GLP1R (0.38) GLP1RGRM5
SCHEMBL23363259 0.74 HTR2C (0.44) GLP1R
SCHEMBL29664028 0.74 HTR2C (0.44) GLP1R
Hydrochloric Acid SCHEMBL31479953 0.73 HTR2C (0.45) GLP1R
Trifluoroacetic Acid SCHEMBL30798083 0.72 RXRA (0.34) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024028795-A1 HETEROBICYCLIC COMPOUNDS AS ORAL GLP1R AGONISTS ZYDUS LIFESCIENCES LIMITED (IN) 2024-02-08 — — WO disclosed