Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | USP1 | O94782 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30798276 | 0.88 | JAK2 (0.36) | GLP1RJAK2TYK2 | |
| Trifluoroacetic Acid SCHEMBL30798007 | 0.87 | GRM2 (0.35) | GLP1RRXRAGRIN1GRIN2BGRM2 | |
| SCHEMBL30798134 | 0.76 | SLC34A1 (0.40) | GLP1R | |
| Trifluoroacetic Acid SCHEMBL30797992 | 0.74 | GLP1R (0.34) | GLP1RGRM5 | |
| Trifluoroacetic Acid SCHEMBL30798083 | 0.73 | RXRA (0.34) | RXRAGRIN1GRIN2BGRM2GRM3 | |
| Trifluoroacetic Acid SCHEMBL25272721 | 0.72 | GLP1R (0.42) | GLP1RGRM2GRM3 | |
| Trifluoroacetic Acid SCHEMBL30404349 | 0.72 | GLP1R (0.42) | GLP1RGRM2GRM3 | |
| Trifluoroacetic Acid SCHEMBL29695902 | 0.70 | HRH4 (0.47) | GRM2GRM3 | |
| SCHEMBL30798126 | 0.70 | GLP1R (0.44) | GLP1R | |
| Trifluoroacetic Acid SCHEMBL29928889 | 0.69 | HRH4 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028795-A1 | HETEROBICYCLIC COMPOUNDS AS ORAL GLP1R AGONISTS | ZYDUS LIFESCIENCES LIMITED (IN) | 2024-02-08 | — | — | WO | disclosed |