Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | GLP1R | P43220 | 14/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30468784 | 0.84 | GPR119 (0.46) | PDE10AGLP1RGPR119 | |
| SCHEMBL27111251 | 0.83 | GLP1R (0.49) | PDE10AGLP1RGPR119 | |
| SCHEMBL22391958 | 0.83 | GLP1R (0.47) | PDE10AGLP1RGPR119 | |
| SCHEMBL29947339 | 0.83 | GLP1R (0.47) | PDE10AGLP1RGPR119 | |
| SCHEMBL20266521 | 0.80 | GPR119 (0.56) | PDE10AGLP1RGPR119 | |
| SCHEMBL29556921 | 0.80 | GPR119 (0.56) | PDE10AGLP1RGPR119 | |
| SCHEMBL27111216 | 0.79 | GPR119 (0.51) | PDE10AGLP1RGPR119 | |
| SCHEMBL30468789 | 0.79 | GPR119 (0.45) | PDE10AGLP1RGPR119 | |
| SCHEMBL27111225 | 0.79 | GPR119 (0.56) | PDE10AGLP1RGPR119 | |
| SCHEMBL22391565 | 0.79 | PDE10A (0.42) | PDE10AGLP1RGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028795-A1 | HETEROBICYCLIC COMPOUNDS AS ORAL GLP1R AGONISTS | ZYDUS LIFESCIENCES LIMITED (IN) | 2024-02-08 | — | — | WO | disclosed |