Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29924769 | 0.90 | CYP1A2 (0.38) | MAPT | |
| SCHEMBL25004893 | 0.90 | CYP1A2 (0.38) | MAPT | |
| SCHEMBL27237114 | 0.87 | LMNA (0.32) | — | |
| SCHEMBL30882773 | 0.87 | LMNA (0.35) | PTGER4PPARG | |
| SCHEMBL25005199 | 0.87 | LMNA (0.35) | PTGER4PPARG | |
| SCHEMBL29946034 | 0.80 | ACSS2 (0.43) | — | |
| SCHEMBL25340079 | 0.80 | ACSS2 (0.43) | — | |
| SCHEMBL30798199 | 0.78 | TP53 (0.44) | PTGER4MAPT | |
| SCHEMBL31143242 | 0.77 | MAPT (0.38) | PTGER4PPARGMAPT | |
| SCHEMBL31143304 | 0.77 | MAPT (0.38) | PTGER4PPARGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117986264-A | Benzo nitrogen-containing polycyclic derivative regulator and preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |