Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 6/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR1E | P28566 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5720837 | 0.85 | HDAC1 (0.40) | KMT2AMAPK1L3MBTL1NAMPTHTT | |
| SCHEMBL31323827 | 0.81 | TMEM97 (0.47) | TMEM97SIGMAR1MEN1KMT2ADHFR | |
| SCHEMBL22873338 | 0.81 | MEN1 (0.36) | TMEM97SIGMAR1HRH1HRH3HTR1A | |
| SCHEMBL24507074 | 0.81 | SCD (0.44) | HTR2CKMT2AMAPK1L3MBTL1NAMPT | |
| SCHEMBL16841678 | 0.80 | DPP4 (0.48) | MEN1KMT2ANAMPT | |
| SCHEMBL20046636 | 0.78 | GPR119 (0.43) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL1842426 | 0.76 | MEN1 (0.61) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL23794851 | 0.76 | DHFR (0.46) | TMEM97SIGMAR1HRH1HRH3HTR1A | |
| SCHEMBL25167562 | 0.75 | SMN1; SMN2 (0.46) | TMEM97SIGMAR1HRH1HRH3HTR1A | |
| SCHEMBL25172506 | 0.75 | TMEM97 (0.46) | TMEM97SIGMAR1HRH1HRH3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024028795-A1 | HETEROBICYCLIC COMPOUNDS AS ORAL GLP1R AGONISTS | ZYDUS LIFESCIENCES LIMITED (IN) | 2024-02-08 | — | — | WO | disclosed |