Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | SIK1 | P57059 | 1/20 | 0.43 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.43 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2024212 | 1.00 | POLB (0.46) | POLBTSHRAPOBEC3AHTTAPOBEC3G | |
| SCHEMBL2025732 | 0.84 | PIM1 (0.47) | POLBMAPTHSD17B10ERN1KDM4E | |
| SCHEMBL1104463 | 0.82 | POLB (0.48) | POLBMAPTKDM4ECYP3A4ALDH1A1 | |
| SCHEMBL29927434 | 0.82 | CYP3A4 (0.49) | POLBMAPTERN1KDM4EGAA | |
| SCHEMBL2024646 | 0.82 | CYP3A4 (0.49) | POLBMAPTERN1KDM4EGAA | |
| SCHEMBL22093825 | 0.81 | DGAT1 (0.43) | POLBTSHRAPOBEC3AHTTAPOBEC3G | |
| SCHEMBL347917 | 0.80 | CYP3A4 (0.51) | POLBMAPTMKNK2HSD17B10KDM4E | |
| SCHEMBL18511829 | 0.79 | MAPT (0.41) | TSHRAPOBEC3AHTTAPOBEC3GMAPT | |
| SCHEMBL27044789 | 0.79 | RECQL (0.41) | MAPTSIK1SIK2SIK3ERN1 | |
| SCHEMBL5329670 | 0.79 | MAP2K1 (0.50) | POLBTSHRAPOBEC3AHTTAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323352-A1 | MODULATORS OF BCL6 PROTEOLYSIS AND ASSOCIATED METHODS OF USE | Arvinas Operations, Inc. (US) | 2024-02-21 | — | — | EP | disclosed |