Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778228 | 0.84 | CA12 (0.46) | MAP2K1POLBKDM4ETDP1MAPT | |
| SCHEMBL16510666 | 0.84 | CYP3A4 (0.51) | MAP2K1GAACYP3A4SLC6A9HTT | |
| SCHEMBL17124305 | 0.82 | POLB (0.48) | MAP2K1POLBKDM4EMAPTCYP1A2 | |
| SCHEMBL3019239 | 0.82 | CYP3A4 (0.42) | MAP2K1KDM4EMAPTL3MBTL1HPGD | |
| SCHEMBL347917 | 0.80 | CYP3A4 (0.51) | POLBMKNK2HSD17B10GAAKDM4E | |
| SCHEMBL18511839 | 0.79 | SLC6A9 (0.39) | MAP2K1POLBKDM4ETDP1MAPT | |
| SCHEMBL2024212 | 0.79 | POLB (0.46) | POLBMKNK2HSD17B10GAAKDM4E | |
| SCHEMBL30798286 | 0.79 | POLB (0.46) | POLBMKNK2HSD17B10GAAKDM4E | |
| SCHEMBL5329614 | 0.78 | MAP2K1 (0.47) | MAP2K1POLBMKNK2KDM4ETDP1 | |
| SCHEMBL1004368 | 0.75 | ACHE (0.48) | POLBMKNK2HSD17B10GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147836-A1 | GLYCINE TRANSPORTER INHIBITING COMPOUNDS AND USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2007-12-27 | — | — | WO | disclosed |