Carbamic Acid

Carbamic Acid

SCHEMBL30798679

CC(C)(C)c1cc(OC(F)F)c(C#N)cc1[N+](=O)[O-].NC(=O)O

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 1/20 0.34
HTT P42858 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
GALR3 O60755 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
F11 P03951 1/20 0.33
KLKB1 P03952 1/20 0.33
LMNA P02545 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MAPT P10636 1/20 0.31
FBP1 P09467 1/20 0.31
AR P10275 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Carbamic Acid SCHEMBL30798866 0.79 HTT (0.39) VCAM1HTTMEN1KMT2ASMN1; SMN2
SCHEMBL28603822 0.79 VCAM1 (0.37) VCAM1HTTMEN1KMT2ASMN1; SMN2
Carbamic Acid SCHEMBL28603825 0.75 VCAM1 (0.47) VCAM1HTTMEN1KMT2ASMN1; SMN2
SCHEMBL19554332 0.68 VCAM1 (0.50) VCAM1HTTMEN1KMT2ASMN1; SMN2
Carbamic Acid SCHEMBL30798613 0.68 ALDH1A1 (0.42) HTTALDH1A1TSHRTDP1MAPT
SCHEMBL22954112 0.65 CYP2D6 (0.43) ALDH1A1AR
Carbamic Acid SCHEMBL30763483 0.64 ALDH1A1 (0.45) KMT2ASMN1; SMN2L3MBTL1LMNAALDH1A1
SCHEMBL29417219 0.64 SLC6A2 (0.38) ALDH1A1MAPTAR
SCHEMBL7640581 0.64 MAPT (0.58) VCAM1HTTMEN1KMT2AL3MBTL1
SCHEMBL29551672 0.64 ALDH1A1 (0.40) HTTMEN1KMT2ASMN1; SMN2GALR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113166156-B Tyrosine kinase inhibitors, compositions and methods 贝达药业股份有限公司 2024-02-27 CN disclosed