SCHEMBL30798852

SCHEMBL30798852

CC[C@H](C)[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCCN)C(N)=O)C(C)C

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 2/20 0.49
▸ ACE P12821 2/20 0.49
▸ NTSR2 O95665 1/20 0.49
▸ NTSR1 P30989 1/20 0.49
▸ NPY4R P50391 5/20 0.47
▸ NPY1R P25929 4/20 0.47
▸ NPY2R P49146 4/20 0.47
▸ NPY5R Q15761 4/20 0.47
▸ PLG P00747 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30063663 0.93 NTSR2 (0.54) F2ACENTSR2NTSR1NPY4R
SCHEMBL29974534 0.88 NTSR2 (0.54) F2NTSR2NTSR1NPY4RNPY1R
SCHEMBL29974987 0.88 NTSR2 (0.54) F2NTSR2NTSR1NPY4RNPY1R
SCHEMBL30405655 0.88 ACE (0.50) F2ACENTSR2NTSR1NPY4R
SCHEMBL30682522 0.87 NPY4R (0.54) NPY4RNPY1RNPY2RNPY5R
SCHEMBL30450371 0.87 F2 (0.57) F2PLG
SCHEMBL29974829 0.85 F2 (0.52) F2NTSR2NTSR1
SCHEMBL29429777 0.85 GHSR (0.56) F2PLG
SCHEMBL11044131 0.85 OPRK1 (0.53) NPY4RNPY1RNPY2RNPY5R
SCHEMBL11043731 0.85 OPRK1 (0.53) NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240116984-A1 MODIFIED PEPTIDES FOR THE INHIBITION OF ABNORMAL TAU ACCUMULATION NATIONAL SCIENCE FOUNDATION 2024-04-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240116984-A1 MODIFIED PEPTIDES FOR THE INHIBITION OF ABNORMAL TAU ACCUMULATION PRNP, MAPT, APP F2 3097/4885ACE 3820/4885NTSR2 1511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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