Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18629792 | 0.81 | TTR (0.47) | TTRALDH1A1SMN1; SMN2HPGDESR1 | |
| SCHEMBL30848123 | 0.80 | ERN1 (0.35) | ERN1ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL12724992 | 0.79 | TTR (0.41) | ERN1TTRALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL21837082 | 0.79 | TTR (0.72) | ERN1TTRALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL30848213 | 0.78 | ERN1 (0.34) | ERN1ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL30848416 | 0.78 | ERN1 (0.34) | ERN1ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL8572282 | 0.78 | CES2 (0.56) | ERN1ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL850387 | 0.78 | ERN1 (0.44) | ERN1ALDH1A1SMN1; SMN2HPGDESR1 | |
| SCHEMBL144208 | 0.78 | ERN1 (0.48) | ERN1ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL23111999 | 0.77 | TTR (0.47) | ERN1TTRALDH1A1SMN1; SMN2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |
| WO-2024051354-A1 | BENZIMIDAZOLE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州沪云新药研发股份有限公司 | 2024-03-14 | — | — | WO | disclosed |