Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ACLY | P53396 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848187 | 0.82 | TTR (0.46) | SMN1; SMN2ALDH1A1HPGDHDAC1HDAC6 | |
| SCHEMBL29172054 | 0.82 | TTR (0.46) | SMN1; SMN2ALDH1A1HPGDHDAC1HDAC6 | |
| SCHEMBL29171886 | 0.81 | HTT (0.41) | POLBSMN1; SMN2ALDH1A1HDAC1HDAC6 | |
| SCHEMBL30848020 | 0.81 | HTT (0.41) | POLBSMN1; SMN2ALDH1A1HDAC1HDAC6 | |
| SCHEMBL30798877 | 0.78 | ERN1 (0.44) | ERN1POLBSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL29171871 | 0.78 | NOTUM (0.48) | POLBALDH1A1PDK2L3MBTL1 | |
| SCHEMBL30848332 | 0.78 | MAPT (0.34) | HPGDL3MBTL1 | |
| SCHEMBL1002662 | 0.76 | ERN1 (0.42) | ERN1POLBSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL30848123 | 0.73 | ERN1 (0.35) | ERN1POLBSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL29172074 | 0.72 | KMT2A (0.40) | SMN1; SMN2ALDH1A1HPGDRIPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |