Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | CMA1 | P23946 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29776265 | 0.76 | SIGMAR1 (0.39) | LMNAPOLBSIGMAR1CYP19A1ALDH1A1 | |
| SCHEMBL8376402 | 0.69 | SIGMAR1 (0.43) | LMNAPOLBSIGMAR1MC4RCYP19A1 | |
| SCHEMBL6621542 | 0.64 | SIGMAR1 (0.52) | LMNAPOLBSIGMAR1MC4RALDH1A1 | |
| SCHEMBL804232 | 0.63 | GRM2 (0.42) | ALDH1A1ACHEGAATSHRF2 | |
| SCHEMBL28946773 | 0.63 | POLB (0.50) | LMNAPOLBSIGMAR1MC4RALDH1A1 | |
| SCHEMBL15993885 | 0.63 | GAA (0.46) | LMNAPOLBSIGMAR1MC4RALDH1A1 | |
| SCHEMBL25379874 | 0.62 | LMNA (0.41) | LMNAPOLBSIGMAR1MC4RALDH1A1 | |
| SCHEMBL1076822 | 0.62 | SIGMAR1 (0.53) | LMNAPOLBSIGMAR1MC4RACHE | |
| SCHEMBL5694910 | 0.62 | SIGMAR1 (0.48) | LMNAPOLBSIGMAR1MC4RCYP19A1 | |
| SCHEMBL13801222 | 0.61 | SIGMAR1 (0.60) | LMNAPOLBSIGMAR1MC4RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573088-A1 | HETEROCYCLE RBM39 MODULATORS | Recursion Pharmaceuticals, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024039689-A1 | HETEROCYCLE RBM39 MODULATORS | RECURSION PHARMACEUTICALS, INC. (US) | 2024-02-22 | — | — | WO | disclosed |