Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.88 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.88 |
| ▸ | NPC1 | O15118 | 5/20 | 0.88 |
| ▸ | RAB9A | P51151 | 5/20 | 0.88 |
| ▸ | KCNK3 | O14649 | 4/20 | 0.87 |
| ▸ | HPGD | P15428 | 1/20 | 0.81 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | CASP3 | P42574 | 1/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.69 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.63 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643220 | 1.00 | MEN1 (0.88) | MEN1KMT2ANPC1RAB9AKCNK3 | |
| SCHEMBL23447715 | 0.89 | NPC1 (1.00) | MEN1KMT2ANPC1RAB9AKCNK3 | |
| SCHEMBL30739642 | 0.89 | KMT2A (0.86) | MEN1KMT2ANPC1RAB9AKCNK3 | |
| SCHEMBL1811680 | 0.88 | L3MBTL1 (0.82) | MEN1KMT2ANPC1RAB9AKCNK3 | |
| SCHEMBL6802691 | 0.88 | KMT2A (0.78) | MEN1KMT2ANPC1RAB9AKCNK3 | |
| Hydrochloric Acid SCHEMBL2106088 | 0.87 | L3MBTL1 (0.80) | MEN1KMT2ANPC1RAB9AKCNK3 | |
| SCHEMBL8374911 | 0.87 | HDAC1 (0.85) | MEN1KMT2ANPC1RAB9AKCNK3 | |
| SCHEMBL5375629 | 0.86 | NPC1 (0.72) | MEN1KMT2ANPC1RAB9AKCNK3 | |
| SCHEMBL8770869 | 0.86 | KMT2A (0.72) | MEN1KMT2ANPC1RAB9AKCNK3 | |
| SCHEMBL5168239 | 0.86 | PGR (0.72) | MEN1KMT2ANPC1RAB9AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109180518-B | Secondary/tertiary amide compound and synthesis method thereof | 陕西科技大学 | 2021-05-18 | — | — | CN | disclosed |
| CN-109180518-A | Secondary/teritary amide class the compound of one kind and its synthetic method | 陕西科技大学 | 2019-01-11 | — | — | CN | disclosed |
| EP-2757885-A1 | CERTAIN CHEMICAL ENTITES, COMPOSITIONS, AND METHODS | Neupharma, Inc. (US) | 2014-07-30 | — | — | EP | disclosed |
| WO-2013043935-A1 | CERTAIN CHEMICAL ENTITES, COMPOSITIONS, AND METHODS | NEUPHARMA, INC. (US) | 2013-03-28 | — | — | WO | disclosed |
| EP-1677786-A1 | 5-SUBSTITUTED 2-(PHENYLMETHYL)THIO-4-PHENYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND RELATED COMPOUNDS AS GABA-AGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE AND RELATED DISEASES | Bayer HealthCare AG (DE) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005039569-A1 | 5-SUBSTITUTED 2-(PHENYLMETHYL) THIO-4-PHENYL-4H-1,2,4-TRIAZOLE DERIVATIVES AND RELATED COMPOUNDS AS GABA-AGONISTS FOR THE TREATMENT OF URINARY INCONTINENCE AND RELATED DISEASES | BAYER HEALTHCARE AG (DE) | 2005-05-06 | — | — | WO | disclosed |