Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30799358 | 0.85 | SSTR4 (0.33) | SSTR4USP30 | |
| SCHEMBL1181827 | 0.81 | SSTR4 (0.36) | SSTR4USP30GAA | |
| SCHEMBL21872756 | 0.78 | SSTR4 (0.32) | SSTR4 | |
| SCHEMBL21873820 | 0.78 | SSTR4 (0.34) | SSTR4 | |
| SCHEMBL30799546 | 0.77 | SOS1 (0.36) | SSTR4USP30SOS1 | |
| SCHEMBL30799310 | 0.77 | SSTR4 (0.33) | SSTR4USP30SOS1 | |
| SCHEMBL21872667 | 0.76 | NFKB1 (0.32) | SSTR4 | |
| SCHEMBL22885615 | 0.75 | SSTR4 (0.33) | SSTR4USP30 | |
| SCHEMBL31453148 | 0.74 | SSTR4 (0.41) | SSTR4USP30 | |
| SCHEMBL15058027 | 0.74 | SSTR4 (0.32) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114853730-B | Compounds used as HPK1 kinase inhibitor, preparation method and application thereof | 中国药科大学 | 2024-03-26 | — | — | CN | disclosed |