Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | GRK5 | P34947 | 1/20 | 0.41 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27544807 | 0.79 | SOAT1 (0.40) | SOAT1SIGMAR1MAPK1MEN1KMT2A | |
| SCHEMBL2822825 | 0.72 | PARP3 (0.46) | SOAT1SIGMAR1MEN1KMT2A | |
| SCHEMBL29110224 | 0.71 | HTT (0.46) | CYP1A2TSHRCYP2C19 | |
| SCHEMBL11765843 | 0.68 | SIGMAR1 (0.45) | SIGMAR1 | |
| SCHEMBL31451062 | 0.68 | HDAC4 (0.59) | EPHX1SIGMAR1MAPK1MEN1KMT2A | |
| SCHEMBL13975670 | 0.68 | HDAC4 (0.59) | EPHX1SIGMAR1MAPK1MEN1KMT2A | |
| SCHEMBL29127675 | 0.68 | SIGMAR1 (0.41) | SOAT1SIGMAR1 | |
| SCHEMBL11746674 | 0.67 | SLC18A3 (0.57) | EPHX1ALOX15SLC18A3 | |
| SCHEMBL7891735 | 0.67 | MEN1 (0.44) | MAPK1MEN1KMT2AMTNR1AMTNR1B | |
| SCHEMBL8045772 | 0.67 | ALDH1A1 (0.41) | CAMK2AMEN1KMT2ACYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894141-B | Method for synthesizing acyl indene alkane derivative | 贺州学院 | 2023-12-22 | — | — | CN | disclosed |