Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNPAT | O15228 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.40 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31244871 | 0.87 | FOLH1 (0.39) | GNPATFOLH1RIMKLANAALAD2NOD1 | |
| SCHEMBL30096284 | 0.86 | GNPAT (0.44) | GNPATMMEFOLH1RIMKLANAALAD2 | |
| SCHEMBL27599412 | 0.86 | FOLH1 (0.58) | GNPATFOLH1RIMKLANAALAD2ENPEP | |
| SCHEMBL18557284 | 0.86 | FOLH1 (0.58) | GNPATFOLH1RIMKLANAALAD2ENPEP | |
| SCHEMBL1276949 | 0.86 | FOLH1 (0.58) | GNPATFOLH1RIMKLANAALAD2ENPEP | |
| SCHEMBL1276945 | 0.86 | FOLH1 (0.58) | GNPATFOLH1RIMKLANAALAD2ENPEP | |
| SCHEMBL10165828 | 0.86 | FOLH1 (0.58) | GNPATFOLH1RIMKLANAALAD2ENPEP | |
| SCHEMBL30760990 | 0.86 | FOLH1 (0.58) | GNPATFOLH1RIMKLANAALAD2ENPEP | |
| SCHEMBL28462912 | 0.85 | MME (0.56) | GNPATMME | |
| SCHEMBL30095963 | 0.85 | MME (0.56) | GNPATMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | CTNNB1, APC, CTNNA1 | GNPAT 3689/4885MME 467/4885FOLH1 800/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.