Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 12/20 | 0.54 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31181197 | 0.96 | BACE1 (0.54) | BACE1CTSDGNPATOPRK1 | |
| SCHEMBL29794844 | 0.95 | BACE1 (0.57) | BACE1CTSD | |
| SCHEMBL30799817 | 0.94 | MMP2 (0.55) | GNPATMMP2OPRK1 | |
| SCHEMBL31482981 | 0.93 | MMP2 (0.57) | BACE1GNPATMMP2 | |
| SCHEMBL31554972 | 0.92 | MMP2 (0.56) | BACE1GNPATMMP2OPRK1 | |
| SCHEMBL30497073 | 0.92 | MMP2 (0.56) | BACE1GNPATMMP2OPRK1 | |
| SCHEMBL30799335 | 0.92 | MMP2 (0.55) | BACE1CTSDGNPATMMP2OPRK1 | |
| SCHEMBL30799698 | 0.91 | BACE1 (0.57) | BACE1CTSDMMP2OPRK1 | |
| SCHEMBL30688851 | 0.91 | MMP2 (0.57) | BACE1GNPATMMP2OPRK1 | |
| SCHEMBL30688849 | 0.91 | MMP2 (0.57) | BACE1GNPATMMP2OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | CTNNB1, APC, CTNNA1 | BACE1 10/4885CTSD 2704/4885GNPAT 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.