Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | GLA | P06280 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16238134 | 0.88 | ALDH1A1 (0.70) | ALDH1A1HSD17B10KDM4EGLAGAA | |
| SCHEMBL4856080 | 0.84 | ALDH1A1 (0.59) | ALDH1A1HSD17B10KDM4EGLAGAA | |
| SCHEMBL31752331 | 0.82 | KDM4E (0.79) | ALDH1A1HSD17B10KDM4EGLAGAA | |
| SCHEMBL4859874 | 0.82 | ALDH1A1 (0.58) | ALDH1A1HSD17B10KDM4EGLAGAA | |
| SCHEMBL7846644 | 0.82 | KDM4E (0.79) | ALDH1A1HSD17B10KDM4EGLAGAA | |
| SCHEMBL31751211 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HSD17B10KDM4EGLAGAA | |
| SCHEMBL1805430 | 0.78 | LMNA (0.69) | ALDH1A1HSD17B10KDM4EGLAGAA | |
| SCHEMBL1813746 | 0.75 | ALDH1A1 (0.72) | ALDH1A1HSD17B10KDM4EGLAGAA | |
| SCHEMBL16096073 | 0.75 | LMNA (0.48) | ALDH1A1HSD17B10KDM4EGLAGAA | |
| SCHEMBL4858672 | 0.75 | ALDH1A1 (0.72) | ALDH1A1HSD17B10KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117683042-A | Fused tetracyclic compound, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2024-03-12 | — | — | CN | disclosed |