Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.42 |
| ▸ | ECE1 | P42892 | 4/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31447508 | 1.00 | DPP4 (0.42) | DPP4DPP8DPP9ECE1PDCD1LG2 | |
| SCHEMBL10453944 | 0.86 | DPP4 (0.41) | DPP4DPP8DPP9ECE1ERAP2 | |
| SCHEMBL462747 | 0.86 | DPP4 (0.41) | DPP4DPP8DPP9ECE1ERAP2 | |
| SCHEMBL10453448 | 0.86 | DPP4 (0.41) | DPP4DPP8DPP9ECE1ERAP2 | |
| SCHEMBL10454018 | 0.86 | DPP4 (0.41) | DPP4DPP8DPP9ECE1ERAP2 | |
| SCHEMBL1083057 | 0.86 | DPP4 (0.41) | DPP4DPP8DPP9ECE1ERAP2 | |
| SCHEMBL9852025 | 0.86 | MME (0.44) | DPP4DPP8DPP9ECE1PDCD1LG2 | |
| SCHEMBL29517369 | 0.86 | MME (0.44) | DPP4DPP8DPP9ECE1PDCD1LG2 | |
| SCHEMBL29697058 | 0.86 | MME (0.44) | DPP4DPP8DPP9ECE1PDCD1LG2 | |
| SCHEMBL9852027 | 0.86 | MME (0.44) | DPP4DPP8DPP9ECE1PDCD1LG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | PARABILIS MEDICINES, INC. | 2024-04-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240116985-A1 | STAPLED PEPTIDES AND METHODS THEREOF | CTNNB1, APC, CTNNA1 | DPP4 552/4885DPP8 231/4885DPP9 205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.