SCHEMBL9852027

SCHEMBL9852027

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nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.44
ACE P12821 1/20 0.44
CPA1 P15085 1/20 0.44
ACE2 Q9BYF1 1/20 0.44
ECE1 P42892 3/20 0.42
CTSD P07339 1/20 0.42
BACE1 P56817 1/20 0.42
DPP4 P27487 1/20 0.41
DPP8 Q6V1X1 1/20 0.41
DPP9 Q86TI2 1/20 0.41
LTA4H P09960 4/20 0.41
PDCD1LG2 Q9BQ51 1/20 0.40
CD274 Q9NZQ7 1/20 0.40
ANPEP P15144 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29517369 1.00 MME (0.44) MMEACECPA1ACE2ECE1
SCHEMBL9852025 1.00 MME (0.44) MMEACECPA1ACE2ECE1
SCHEMBL29697058 1.00 MME (0.44) MMEACECPA1ACE2ECE1
Hydrochloric Acid SCHEMBL23404070 0.98 MME (0.43) MMEACECPA1ACE2ECE1
Hydrochloric Acid SCHEMBL23404085 0.98 MME (0.43) MMEACECPA1ACE2ECE1
SCHEMBL30629769 0.96 MME (0.42) MMEACECPA1ACE2ECE1
SCHEMBL31169711 0.92 BACE1 (0.51) MMEACECPA1ACE2ECE1
SCHEMBL30068583 0.89 BACE1 (0.44) MMEACECPA1ACE2ECE1
SCHEMBL29696975 0.89 BACE1 (0.44) MMEACECPA1ACE2ECE1
SCHEMBL31447508 0.86 DPP4 (0.42) ECE1CTSDBACE1DPP4DPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 338 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN INC (US) 2026-05-07 US claimed
EP-4713025-A2 DELIVERY OF DUAL PAYLOAD OF MMAF OR MMAE AND TLR7 AGONISTS The Research Foundation for The State University of New York (US) 2026-03-25 EP claimed
US-20250375530-A1 ROR1/EGFR BI-SPECIFIC ANTIGEN BINDING MOLECULES ALMAC DISCOVERY LTD (GB) 2025-12-11 US claimed
US-20250367315-A1 ANTIBODY-DRUG CONJUGATES WITH MASKED PBD DIMERS SYNAFFIX BV (NL) 2025-12-04 US claimed
EP-4637831-A1 ANTIBODY-DRUG CONJUGATES WITH MASKED PBD DIMERS Synaffix B.V. (NL) 2025-10-29 EP claimed
EP-4638722-A2 ALPP-SPECIFIC VARIANT ANTIGEN BINDING MOLECULES Almac Discovery Limited (GB) 2025-10-29 EP claimed
US-20250269051-A1 ROR1-SPECIFIC VARIANT ANTIGEN BINDING MOLECULES ALMAC DISCOVERY LIMITED (GB) 2025-08-28 US claimed
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof IMMUNOGEN, INC. (US) 2025-08-19 US claimed
EP-4543489-A1 ROR1/EGFR BI-SPECIFIC ANTIGEN BINDING MOLECULES Almac Discovery Limited (GB) 2025-04-30 EP claimed
CN-118930362-A Slow-release small-molecule peptide carbon-based fertilizer and composite carbon-based fertilizer with same 北京锦绣新技术发展有限公司 2024-11-12 CN claimed
US-20230094471-A1 CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES IMMUNOGEN, INC. (US) 2023-03-30 US claimed
WO-2022192134-A1 METHODS FOR INCREASING EFFICACY OF IMMUNOCONJUGATES TARGETING ADAM9 FOR THE TREATMENT OF CANCER IMMUNOGEN, INC. (US) 2022-09-15 WO claimed
WO-2022187809-A1 TLR7 AND TLR8 AGONISTS FOR THE TREATMENT OF CANCER AND/OR INFECTIOUS DISEASES THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) 2022-09-09 WO claimed
WO-2022129622-A1 ROR1-SPECIFIC VARIANT ANTIGEN BINDING MOLECULES ALMAC DISCOVERY LIMITED (GB) 2022-06-23 WO claimed
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF IMMUNOGEN SWITZERLAND GMBH (CH) 2022-04-14 US claimed
CN-114222756-A Biparatopic FR-alpha antibodies and immunoconjugates 伊缪诺金公司 2022-03-22 CN claimed
EP-3962935-A1 BIPARATOPIC FR-ALPHA ANTIBODIES AND IMMUNOCONJUGATES Immunogen, Inc. (US) 2022-03-09 EP claimed
CN-114032271-A Oyster polypeptide and polypeptide powder with uric acid reducing effect as well as preparation method and application of oyster polypeptide and polypeptide powder 浙江工业大学 2022-02-11 CN claimed
EP-3941527-A1 METHODS OF PREPARING CELL-BINDING AGENT-DRUG CONJUGATES ImmunoGen, Inc. (US) 2022-01-26 EP claimed
EP-0457314-A1 Nutrient compositions containing peptides CLINTEC NUTRITION COMPANY (US) 1991-11-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12390471-B2 Maytansinoid derivatives with self-immolative peptide linkers and conjugates thereof VIP, AREG, MIF MME 1501/4885ACE 1733/4885CPA1 267/4885
US-20220111067-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VIP, AREG, MIF MME 1501/4885ACE 1733/4885CPA1 267/4885
US-20230094471-A1 CYTOTOXIC BIS-BENZODIAZEPINE DERIVATIVES AND CONJUGATES THEREOF WITH CELL-BINDING AGENTS FOR INHIBITING ABNORMAL CELL GROWTH OR FOR TREATING PROLIFERATIVE DISEASES GABBR2, GABRB1, GABRB2 MME 4355/4885ACE 4608/4885CPA1 3998/4885
US-20250375530-A1 ROR1/EGFR BI-SPECIFIC ANTIGEN BINDING MOLECULES EGFR, ROR1, ERBB2 MME 1736/4885ACE 3913/4885CPA1 2423/4885
US-20250269051-A1 ROR1-SPECIFIC VARIANT ANTIGEN BINDING MOLECULES RORB, RORA, RORC MME 2449/4885ACE 3300/4885CPA1 1409/4885
US-20260124212-A1 MAYTANSINOID DERIVATIVES WITH SELF-IMMOLATIVE PEPTIDE LINKERS AND CONJUGATES THEREOF VEGFA, VIP, AREG MME 961/4885ACE 2255/4885CPA1 238/4885
US-20250367315-A1 ANTIBODY-DRUG CONJUGATES WITH MASKED PBD DIMERS CD22, PBDC1, PA2G4 MME 2428/4885ACE 3923/4885CPA1 3127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.