SCHEMBL3079975

SCHEMBL3079975

C[CH]CCc1cccc(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.57
AOC3 Q16853 1/20 0.53
CHRM2 P08172 1/20 0.51
CHRM1 P11229 1/20 0.51
CHRM3 P20309 1/20 0.51
PNMT P11086 2/20 0.50
HTR3E A5X5Y0 2/20 0.49
HTR3B O95264 2/20 0.49
HTR3A P46098 2/20 0.49
HTR3D Q70Z44 2/20 0.49
HTR3C Q8WXA8 2/20 0.49
CYP3A4 P08684 2/20 0.46
IDO1 P14902 2/20 0.46
AGXT P21549 2/20 0.46
TSHR P16473 1/20 0.45
RECQL P46063 1/20 0.45
C3AR1 Q16581 1/20 0.44
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27427316 0.81 TAAR1 (0.53) TAAR1AOC3CHRM2CHRM1CHRM3
SCHEMBL12050856 0.80 TAAR1 (0.74) TAAR1AOC3CHRM2CHRM1CHRM3
SCHEMBL9131495 0.80 TAAR1 (0.57) TAAR1AOC3CHRM2CHRM1CHRM3
SCHEMBL67484 0.80 TAAR1 (0.57) TAAR1AOC3CHRM2CHRM1CHRM3
SCHEMBL6158701 0.80 TAAR1 (0.57) TAAR1AOC3CHRM2CHRM1CHRM3
SCHEMBL3084924 0.79 PNMT (0.54) TAAR1AOC3CHRM2CHRM1CHRM3
SCHEMBL1985498 0.78 TAAR1 (0.59) TAAR1IDO1
SCHEMBL91272 0.77 TAAR1 (0.63) TAAR1AOC3CHRM2CHRM1CHRM3
SCHEMBL29848342 0.77 TAAR1 (0.63) TAAR1AOC3CHRM2CHRM1CHRM3
SCHEMBL5241228 0.76 TAAR1 (0.68) TAAR1AOC3CHRM2PNMTHTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100234220-A1 Oxooxetanes as Fungicidal Agents BAYER CROPSCIENCE AG (DE) 2010-09-16 US disclosed
CN-1119337-C Substituted 2, 4-diamino-1, 3, 5-triazines as herbicides BAYER AG (DE) 2003-08-27 CN disclosed
CN-1239957-A Substituting 2-amino-4-alkylamino-1,3,5-triazine as herbicide BAYER AG (DE) 1999-12-29 CN disclosed
CN-1239955-A Substituted 2, 4-diamino-1, 3, 5-triazines as herbicides BAYER AG (DE) 1999-12-29 CN disclosed
CN-1044365-C Alpha, omega-diarylalkane derivatives, their preparation and their use in the treatment and prevention of circulatory diseases and psychosis SANKYO CO (JP) 1999-07-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100234220-A1 Oxooxetanes as Fungicidal Agents CYP51A1, PNPO, AOX1 TAAR1 2890/4885AOC3 9/4885CHRM2 2490/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.