Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | LATS2 | Q9NRM7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3515522 | 0.76 | ALDH1A1 (0.41) | MAPTPDGFRBPDGFRAKDM4EMEN1 | |
| SCHEMBL27796045 | 0.76 | KDM4E (0.43) | MAPTGSK3BSYKKDM4EALDH1A1 | |
| SCHEMBL23684063 | 0.71 | ALDH1A1 (0.56) | KDM4EMEN1ALDH1A1KMT2AHCAR3 | |
| SCHEMBL18980782 | 0.70 | MAPT (0.47) | MAPTGSK3BSYKACKR3DHODH | |
| SCHEMBL30472838 | 0.69 | CYP11B2 (0.59) | MAPTPDGFRBPDGFRAKDM4EKMT2A | |
| SCHEMBL23562825 | 0.69 | PIK3CB (0.49) | MAPTGSK3BCYP11B2 | |
| SCHEMBL11169098 | 0.69 | EPHX1 (0.49) | MAPTGSK3BKDM4EMEN1APAF1 | |
| SCHEMBL22574279 | 0.68 | SMYD3 (0.43) | KDM4EMEN1ALDH1A1KMT2AROCK2 | |
| SCHEMBL19984693 | 0.68 | PDGFRB (0.40) | MAPTPDGFRBPDGFRAKDM4EMEN1 | |
| SCHEMBL27937316 | 0.68 | ALDH1A1 (0.56) | KDM4EMEN1ALDH1A1KMT2AHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117865941-A | Substituted piperidine compounds, process for their preparation and their use | 上海方予健康医药科技有限公司 | 2024-04-12 | — | — | CN | disclosed |