Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 13/20 | 0.46 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.46 |
| ▸ | TRAP1 | Q12931 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24321244 | 1.00 | MEN1 (0.46) | MEN1KMT2AHSP90AA1HSP90B1TRAP1 | |
| SCHEMBL16569651 | 0.90 | HSP90AA1 (0.44) | MEN1KMT2AHSP90AA1HSP90B1TRAP1 | |
| SCHEMBL24321693 | 0.89 | PDK1 (0.44) | MEN1KMT2AHSP90AA1HSP90B1TRAP1 | |
| SCHEMBL24321350 | 0.87 | MEN1 (0.47) | MEN1KMT2AHSP90AA1HSP90B1TRAP1 | |
| SCHEMBL24321184 | 0.86 | HSP90AA1 (0.46) | MEN1KMT2AHSP90AA1HSP90B1TRAP1 | |
| SCHEMBL16569200 | 0.85 | KDM4E (0.42) | MEN1KMT2AHSP90AA1KDM4EALDH1A1 | |
| SCHEMBL24321134 | 0.85 | HSP90AA1 (0.47) | MEN1KMT2AHSP90AA1HSP90B1KDM4E | |
| SCHEMBL22541170 | 0.85 | HSP90AA1 (0.48) | HSP90AA1HSP90AB1 | |
| SCHEMBL24321700 | 0.85 | HSP90AA1 (0.44) | HSP90AA1HSP90B1TRAP1KDM4EALDH1A1 | |
| SCHEMBL18561685 | 0.85 | HSP90AA1 (0.40) | MEN1KMT2AHSP90AA1HSP90B1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025019666-A1 | METHODS AND COMPOSITIONS FOR MODULATING SHP2 | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2025-01-23 | — | — | WO | disclosed |
| WO-2024044334-A2 | METHODS AND COMPOSITIONS FOR MODULATING KRAS(G12D) | RANOK THERAPEUTICS (HANGZHOU) CO. LTD. (CN) | 2024-02-29 | — | — | WO | disclosed |