Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 10/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16569651 | 0.95 | HSP90AA1 (0.44) | MEN1KMT2AHSP90AA1HSP90AB1 | |
| SCHEMBL24321350 | 0.93 | MEN1 (0.47) | KDM4EALDH1A1TDP1MEN1TSHR | |
| SCHEMBL18561685 | 0.93 | HSP90AA1 (0.40) | KDM4EALDH1A1TDP1MEN1TSHR | |
| SCHEMBL24321184 | 0.92 | HSP90AA1 (0.46) | KDM4EALDH1A1TDP1MEN1TSHR | |
| SCHEMBL16569876 | 0.92 | ALDH1A1 (0.44) | ALDH1A1TSHRKMT2AHSP90AA1L3MBTL1 | |
| SCHEMBL24321134 | 0.92 | HSP90AA1 (0.47) | KDM4EALDH1A1TDP1MEN1TSHR | |
| SCHEMBL24321700 | 0.91 | HSP90AA1 (0.44) | KDM4EALDH1A1TDP1HSP90AA1HSP90AB1 | |
| SCHEMBL17293918 | 0.89 | L3MBTL1 (0.40) | KDM4EALDH1A1TDP1MEN1TSHR | |
| SCHEMBL22541300 | 0.89 | HSP90AA1 (0.40) | KDM4EALDH1A1TDP1HSP90AA1HSP90AB1 | |
| SCHEMBL16713228 | 0.88 | HSP90AA1 (0.44) | KDM4EALDH1A1TDP1HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3035938-A1 | TARGETED THERAPEUTICS | Synta Pharmaceuticals Corp. (US) | 2016-06-29 | — | — | EP | disclosed |
| WO-2015038649-A1 | TARGETED THERAPEUTICS | SYNTA PHARMACEUTICALS CORP. (US) | 2015-03-19 | — | — | WO | disclosed |