Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | CPS1 | P31327 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28133059 | 0.78 | GHSR (0.56) | GHSRALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL3457089 | 0.77 | MAPK14 (0.55) | GHSRMAPK14OXTR | |
| SCHEMBL29944074 | 0.77 | GHSR (0.71) | GHSRALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL1355458 | 0.77 | GHSR (0.71) | GHSRALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL29990457 | 0.75 | GHSR (0.67) | GHSRALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL3235960 | 0.75 | GHSR (0.67) | GHSRALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL17443852 | 0.75 | GHSR (0.75) | GHSRALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL16002858 | 0.75 | GHSR (0.58) | GHSRALDH1A1KDM4EHPGDENPP2 | |
| SCHEMBL30801187 | 0.75 | GHSR (0.58) | GHSRALDH1A1 | |
| SCHEMBL31581113 | 0.75 | CCNC (0.51) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693502-A | Compounds for inhibiting or degrading ITK, compositions comprising the same, methods of making the same, and methods of using the same | 纽力克斯治疗公司 | 2024-03-12 | — | — | CN | disclosed |