SCHEMBL3235960

SCHEMBL3235960

O=C(c1ccc2cc[nH]c2c1)N1CCNCC1

nearest known ligand 0.67

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 6/20 0.67
MAPK14 Q16539 2/20 0.61
ALDH1A1 P00352 2/20 0.57
HSD17B10 Q99714 2/20 0.57
HPGD P15428 2/20 0.57
KDM4E B2RXH2 1/20 0.57
ENPP2 Q13822 1/20 0.57
SIGMAR1 Q99720 1/20 0.53
HRH4 Q9H3N8 1/20 0.50
HRH3 Q9Y5N1 1/20 0.50
OXTR P30559 1/20 0.49
GPR183 P32249 1/20 0.49
MAPT P10636 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29990457 1.00 GHSR (0.67) GHSRMAPK14ALDH1A1HSD17B10HPGD
SCHEMBL3386763 0.90 MAPK14 (0.62) GHSRMAPK14SIGMAR1HRH4HRH3
SCHEMBL30066210 0.90 MAPK14 (0.62) GHSRMAPK14SIGMAR1HRH4HRH3
SCHEMBL1355458 0.86 GHSR (0.71) GHSRMAPK14ALDH1A1HSD17B10HPGD
SCHEMBL29944074 0.86 GHSR (0.71) GHSRMAPK14ALDH1A1HSD17B10HPGD
SCHEMBL17443852 0.85 GHSR (0.75) GHSRMAPK14ALDH1A1HSD17B10HPGD
SCHEMBL30801187 0.84 GHSR (0.58) GHSRALDH1A1HRH4
SCHEMBL31428636 0.84 GHSR (0.65) GHSRMAPK14ALDH1A1HSD17B10HPGD
SCHEMBL2207578 0.84 GHSR (0.65) GHSRMAPK14ALDH1A1HSD17B10HPGD
SCHEMBL143751 0.84 GHSR (0.65) GHSRMAPK14ALDH1A1HSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4723888-A2 MIXTURE OF AGRICULTURALLY ACTIVE COMPOUNDS AND SPRAY ADJUVANTS Speedagro Inc. (US) 2026-04-15 EP claimed
WO-2024254580-A2 MIXTURE OF AGRICULTURALLY ACTIVE COMPOUNDS AND SPRAY ADJUVANTS SPEEDAGRO INC. (US) 2024-12-12 WO claimed
CN-113678824-B Micronutrient compositions and systems and methods of use thereof 温菲尔德解决方案公司 2023-10-10 CN claimed
US-20220095612-A1 MICRONUTRIENT COMPOSITIONS AND SYSTEMS AND METHODS OF USING SAME NANOCHEM SOLUTIONS INC 2022-03-31 US claimed
EP-4723888-A2 MIXTURE OF AGRICULTURALLY ACTIVE COMPOUNDS AND SPRAY ADJUVANTS Speedagro Inc. (US) 2026-04-15 EP disclosed
EP-4601471-A1 SUBSTITUTED 5-MEMBERED RINGS AND THEIR USE AS PESTICIDES Corteva Agriscience LLC (US) 2025-08-20 EP disclosed
CN-119731146-A (2, 4-Dichlorophenoxy) acetic acid analogues 科迪华农业科技有限责任公司 2025-03-28 CN disclosed
CN-111466376-B Multifunctional agricultural adjuvant composition 温菲尔德解决方案公司 2025-01-07 CN disclosed
WO-2024254580-A2 MIXTURE OF AGRICULTURALLY ACTIVE COMPOUNDS AND SPRAY ADJUVANTS SPEEDAGRO INC. (US) 2024-12-12 WO disclosed
CN-115403488-B Preparation method of fomesafen 江苏联化科技有限公司 2024-07-19 CN disclosed
WO-2024081762-A1 SUBSTITUTED 5-MEMBERED RINGS AND THEIR USE AS PESTICIDES CORTEVA AGRISCIENCE LLC (US) 2024-04-18 WO disclosed
WO-2024031002-A1 (2,4-DICHLOROPHENOXY)ACETIC ACID ANALOGS CORTEVA AGRISCIENCE LLC (US) 2024-02-08 WO disclosed
US-20120010193-A1 CGRP RECEPTOR ANTAGONISTS MERCK SHARP & DOHME CORP. (US) 2012-01-12 US disclosed
EP-2069331-B1 1H-INDOL-6-YL-PIPERAZIN-1-YL-METHANONE-DERIVATIVES FOR USE AS H3 RECEPTOR MODULATORS HOFFMANN LA ROCHE (CH) 2010-05-05 EP disclosed
EP-2069331-A1 1H-INDOL-6-YL-PIPERAZIN-1-YL-METHANONE-DERIVATIVES FOR USE AS H3 RECEPTOR MODULATORS F.HOFFMANN-LA ROCHE AG (CH) 2009-06-17 EP disclosed
US-7514433-B2 1H-indole-6-yl-piperazin-1-yl-methanone derivatives HOFFMANN-LA ROCHE INC. (US) 2009-04-07 US disclosed
US-7514433-B2 1H-indole-6-yl-piperazin-1-yl-methanone derivatives HOFFMANN-LA ROCHE INC. (US) 2009-04-07 US disclosed
US-20080032976-A1 1H-indole-6-yl-piperazin-1-yl-methanone derivatives F. HOFFMANN-LA ROCHE AG (CH) 2008-02-07 US disclosed
US-20080032976-A1 1H-indole-6-yl-piperazin-1-yl-methanone derivatives F. HOFFMANN-LA ROCHE AG (CH) 2008-02-07 US disclosed
WO-2008015125-A1 1H-INDOL-6-YL-PIPERAZIN-1-YL-METHANONE-DERIVATIVES FOR USE AS H3 RECEPTOR MODULATORS F. HOFFMANN-LA ROCHE AG (CH) 2008-02-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120010193-A1 CGRP RECEPTOR ANTAGONISTS BDKRB1, BDKRB2, CALCRL GHSR 239/4885MAPK14 4714/4885ALDH1A1 1870/4885
US-20080032976-A1 1H-indole-6-yl-piperazin-1-yl-methanone derivatives HTR6, HTR1A, HRH4 GHSR 185/4885MAPK14 2794/4885ALDH1A1 292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.