Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 7/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29207728 | 1.00 | GPR119 (0.39) | GPR119MCHR1DDB1CRBNMAPT | |
| SCHEMBL26113213 | 0.83 | PDE10A (0.43) | GPR119MCHR1DDB1CRBNMAPT | |
| SCHEMBL22119850 | 0.81 | GPR119 (0.54) | GPR119MCHR1DDB1CRBNMAPT | |
| Hydrochloric Acid SCHEMBL28627284 | 0.80 | GPR119 (0.53) | GPR119MCHR1DDB1CRBNMAPT | |
| SCHEMBL22119864 | 0.76 | ALDH1A1 (0.49) | DDB1CRBNMAPT | |
| SCHEMBL23816515 | 0.74 | CRBN (0.45) | GPR119DDB1CRBN | |
| SCHEMBL30064072 | 0.74 | CRBN (0.45) | GPR119DDB1CRBN | |
| SCHEMBL24670654 | 0.71 | AKR1C3 (0.48) | GPR119MAPT | |
| SCHEMBL10224799 | 0.71 | GPR119 (0.53) | GPR119MAPT | |
| SCHEMBL24735177 | 0.71 | MAPT (0.40) | GPR119MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117693502-A | Compounds for inhibiting or degrading ITK, compositions comprising the same, methods of making the same, and methods of using the same | 纽力克斯治疗公司 | 2024-03-12 | — | — | CN | disclosed |