Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 15/20 | 0.49 |
| ▸ | KAT7 | O95251 | 14/20 | 0.49 |
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | KAT6B | Q8WYB5 | 8/20 | 0.43 |
| ▸ | KAT5 | Q92993 | 4/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 4/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25045847 | 1.00 | KAT6A (0.49) | KAT6AKAT7BRD4KAT6BKAT5 | |
| SCHEMBL25926367 | 0.90 | KAT6A (0.49) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL25562267 | 0.80 | KAT6A (0.49) | KAT6AKAT7BRD4KAT6BKAT5 | |
| SCHEMBL30360809 | 0.80 | KAT6A (0.49) | KAT6AKAT7BRD4KAT6BKAT5 | |
| SCHEMBL25926263 | 0.79 | KAT6A (0.52) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL29054607 | 0.78 | KAT6A (0.51) | KAT6AKAT7BRD4KAT6BKAT5 | |
| SCHEMBL25926369 | 0.78 | KAT6A (0.48) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL30801369 | 0.77 | KAT7 (0.70) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL25045846 | 0.77 | KAT7 (0.70) | KAT6AKAT7KAT6BKAT5KAT8 | |
| SCHEMBL25926368 | 0.76 | KAT6A (0.49) | KAT6AKAT7KAT6BKAT5KAT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4385989-A1 | SULFONAMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2024-06-19 | — | — | EP | disclosed |
| CN-117597341-A | Sulfonamide derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-02-23 | — | — | CN | disclosed |