Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.43 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801771 | 1.00 | SCD (0.43) | SCDSCD5USP30PRKDCFAAH | |
| SCHEMBL30801891 | 0.87 | NPC1 (0.37) | SCDSCD5DRD3ALDH1A1HPGD | |
| SCHEMBL23574035 | 0.85 | USP30 (0.49) | SCDSCD5USP30PRKDCFAAH | |
| SCHEMBL23574030 | 0.85 | USP30 (0.49) | SCDSCD5USP30PRKDCFAAH | |
| SCHEMBL23574028 | 0.85 | USP30 (0.49) | SCDSCD5USP30PRKDCFAAH | |
| SCHEMBL30801785 | 0.84 | GRIN1 (0.38) | HTR2CALDH1A1TSHR | |
| SCHEMBL30801848 | 0.83 | USP30 (0.39) | SCDSCD5USP30PRKDCDRD2 | |
| SCHEMBL30801748 | 0.83 | USP30 (0.39) | SCDSCD5USP30PRKDCDRD2 | |
| SCHEMBL30801797 | 0.81 | GRM5 (0.47) | USP30CYP1A2CYP3A4XDHCLK4 | |
| SCHEMBL30801839 | 0.80 | USP30 (0.38) | USP30PRKDCDRD2DRD3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |