Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801870 | 0.86 | GRM5 (0.48) | GRM5CYP1A2DPP4USP30LRRK2 | |
| SCHEMBL30801868 | 0.86 | DPP4 (0.42) | GRM5CYP1A2CYP3A4CYP2C19DPP4 | |
| SCHEMBL23573922 | 0.85 | DPP4 (0.49) | GRM5CYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL23573924 | 0.85 | DPP4 (0.49) | GRM5CYP1A2CYP3A4CYP2C19HSD17B10 | |
| SCHEMBL30801790 | 0.81 | USP30 (0.43) | CYP1A2CYP3A4HSD17B10ALOX15USP30 | |
| SCHEMBL30801795 | 0.81 | USP30 (0.43) | CYP1A2CYP3A4HSD17B10ALOX15USP30 | |
| SCHEMBL30801758 | 0.81 | DPP4 (0.39) | CYP1A2HSD17B10DPP4USP30ALDH1A1 | |
| SCHEMBL30801771 | 0.81 | SCD (0.43) | CYP1A2CYP3A4HSD17B10USP30CLK4 | |
| SCHEMBL30801748 | 0.81 | USP30 (0.39) | USP30LRRK2XDH | |
| SCHEMBL30801741 | 0.81 | SCD (0.43) | CYP1A2CYP3A4HSD17B10USP30CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |