Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 5/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30801748 | 1.00 | USP30 (0.39) | USP30XDHCPT2CPT1ADRD2 | |
| SCHEMBL30801744 | 0.87 | NPC1 (0.38) | USP30CPT1AHTR2CHTR2B | |
| SCHEMBL30801830 | 0.86 | CRHBP (0.43) | USP30DRD2HTR2C | |
| SCHEMBL30801805 | 0.86 | CRHBP (0.43) | USP30DRD2HTR2C | |
| SCHEMBL23574019 | 0.85 | USP30 (0.49) | USP30 | |
| SCHEMBL23574101 | 0.85 | USP30 (0.49) | USP30 | |
| SCHEMBL23574018 | 0.85 | USP30 (0.49) | USP30 | |
| SCHEMBL30801750 | 0.84 | PARP1 (0.39) | USP30XDH | |
| SCHEMBL30801850 | 0.84 | USP30 (0.39) | USP30HTR2CHTR2B | |
| SCHEMBL30801741 | 0.83 | SCD (0.43) | USP30XDHCPT2CPT1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |