Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.44 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2177544 | 0.86 | BRD4 (0.48) | MAPTHTTFGFR4NPC1RAB9A | |
| SCHEMBL3643232 | 0.85 | MAPT (0.53) | MAPTHTTHPGDCYP1A2CYP3A4 | |
| SCHEMBL3643236 | 0.85 | MAPT (0.53) | MAPTHTTHPGDCYP1A2CYP3A4 | |
| SCHEMBL27227145 | 0.85 | MAPT (0.54) | MAPTHTTPIN1FGFR4CYP1A2 | |
| SCHEMBL19666538 | 0.83 | PIN1 (0.67) | MAPTPIN1HPGDCYP1A2CYP3A4 | |
| SCHEMBL2195898 | 0.82 | MAPT (0.51) | MAPTHTTPIN1FGFR4CYP1A2 | |
| SCHEMBL27227387 | 0.82 | GSK3A (0.59) | MAPTHTTPIN1FGFR4NPC1 | |
| SCHEMBL13570773 | 0.82 | MAPT (0.52) | MAPTHTTPIN1FGFR4CYP1A2 | |
| SCHEMBL718271 | 0.80 | MAPT (0.51) | MAPTHTTPIN1FGFR4CYP1A2 | |
| SCHEMBL9984006 | 0.80 | MAPT (0.55) | MAPTHTTPIN1FGFR4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054512-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-03-14 | — | — | WO | disclosed |