Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.51 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.51 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.51 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22719050 | 0.88 | MAPT (0.54) | MAPTMEN1KMT2AMAPK1FGFR4 | |
| SCHEMBL29535826 | 0.88 | MAPT (0.54) | MAPTMEN1KMT2AMAPK1FGFR4 | |
| SCHEMBL9984336 | 0.87 | MAPT (0.52) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL718271 | 0.85 | MAPT (0.51) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL12705359 | 0.85 | FGFR4 (0.52) | MAPTMEN1KMT2ATDP1FGFR4 | |
| SCHEMBL1600402 | 0.85 | PIN1 (0.65) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL27227387 | 0.85 | GSK3A (0.59) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL27227145 | 0.85 | MAPT (0.54) | MAPTMEN1KMT2AMAPK1TDP1 | |
| SCHEMBL17077895 | 0.83 | MAPT (0.53) | MAPTMEN1KMT2AGAAMAPK1 | |
| SCHEMBL15653997 | 0.82 | MAPT (0.51) | MAPTMEN1KMT2ATDP1FGFR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110306606-A1 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | DONG WHA PHARM. CO., LTD. (KR) | 2011-12-15 | — | — | US | disclosed |
| EP-2394993-A2 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | Dong Wha Pharm. Co., Ltd. (KR) | 2011-12-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110306606-A1 | NOVEL 2,6-SUBSTITUTED-3-NITROPYRIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION INCLUDING SAME | NOS3, PTMS, NOS2 | MAPT 4055/4885GUCY1B2 779/4885GUCY1A2 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.