SCHEMBL3080446

SCHEMBL3080446

CC1(C)CC2(CC(C)(C)c3ccc(Oc4ccccc4N)cc32)c2cc(Oc3ccccc3N)ccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.50
RCE1 Q9Y256 1/20 0.50
ALDH1A1 P00352 4/20 0.48
TLR4 O00206 1/20 0.42
IKBKB O14920 2/20 0.38
BRAF P15056 1/20 0.38
LTA4H P09960 1/20 0.37
RXRA P19793 1/20 0.37
RXRB P28702 1/20 0.37
RXRG P48443 1/20 0.37
ADRA2B P18089 1/20 0.36
PTGS1 P23219 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
MAPT P10636 3/20 0.36
CYP3A4 P08684 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CRHBP P24387 1/20 0.36
CRHR2 Q13324 1/20 0.36
LMNA P02545 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7622958 0.87 GAA (0.54) GAARCE1ALDH1A1TLR4IKBKB
SCHEMBL27092144 0.83 ALDH1A1 (0.54) ALDH1A1RXRARXRBRXRGTDP1
SCHEMBL18183534 0.79 GAA (0.39) GAAALDH1A1RXRARXRBRXRG
SCHEMBL203793 0.79 SMN1; SMN2 (0.47) GAAALDH1A1RXRARXRBRXRG
SCHEMBL29608602 0.79 SMN1; SMN2 (0.47) GAAALDH1A1RXRARXRBRXRG
SCHEMBL29521690 0.78 MAOB (0.49) GAAALDH1A1LTA4HRXRARXRB
SCHEMBL204909 0.78 MAOB (0.49) GAAALDH1A1LTA4HRXRARXRB
SCHEMBL31534579 0.78 RXRA (0.43) GAAALDH1A1LTA4HRXRARXRB
SCHEMBL13712348 0.75 PDK2 (0.42) GAAALDH1A1KDM4ELMNACYP1A2
SCHEMBL8014290 0.75 NR4A1 (0.39) RXRARXRBRXRGNR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9728301-B2 Insulated wire and electric or electronic equipment FURUKAWA ELECTRIC CO., LTD. (JP) 2017-08-08 US disclosed
US-20150235736-A1 INSULATED WIRE AND ELECTRIC OR ELECTRONIC EQUIPMENT FURUKAWA MAGNET WIRE CO., LTD. (JP) 2015-08-20 US disclosed
US-20100226016-A1 LIGHT-SHIELDING FILM NIPPON SHOKUBAI CO., LTD. (JP) 2010-09-09 US disclosed
US-6842576-B2 Polymer lightguide NITTO DENKO CORPORATION (JP) 2005-01-11 US disclosed
US-20040234228-A1 Polymer lightguide NITTO DENKO CORPORATION 2004-11-25 US disclosed
US-6103860-A LOW DIELECTRIC CONSTANT, EXCELLENT TRANSPARENCY, LOW HYGROSCOPICITY AND EXCELLENT PROCESSABILITY; SUBSTRATE FOR AN OPTICAL DISK, A PICK-UP LENS, A PLASTIC SUBSTRATE FOR A LIQUID CELL AND A PRISM MITSUI CHEMICALS, INC. (JP) 2000-08-15 US disclosed
US-6080833-A BIS(HYDROXYALKOXYLATED) 1,1'-SPIROBIINDAN POLYCARBONATES AND POLYESTERS POLYMERS AND CURABLE COMPOUNDS SUCH AS BIS(ACRYLATED ALKOXY)SPIROBIINDANS; ALSO POLYAMIDES AND POLYIMIDES CONTAINING SPIROBIINDAN GROUPS MITSUI CHEMICALS, INC. (JP) 2000-06-27 US disclosed
US-5990261-A Organic optical component MITSUI CHEMICALS, INC. (JP) 1999-11-23 US disclosed
EP-0826717-A1 An organic optical component MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-03-04 EP disclosed
EP-0822545-A2 Optical component and spirobiindan polymer therefor MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1998-02-04 EP disclosed