SCHEMBL30804604

SCHEMBL30804604

O=c1ccc2ccc3sccc3c2[nH]1.[Eu+3]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.41
CA9 Q16790 4/20 0.41
HTR1A P08908 6/20 0.37
DRD2 P14416 6/20 0.37
HTR2A P28223 6/20 0.37
CHEK1 O14757 2/20 0.36
GSK3B P49841 2/20 0.36
LIMK1 P53667 2/20 0.36
DYRK1A Q13627 2/20 0.36
CLK4 Q9HAZ1 2/20 0.36
DYRK1B Q9Y463 2/20 0.36
MET P08581 1/20 0.36
AURKA O14965 1/20 0.34
DAPK3 O43293 1/20 0.34
JAK2 O60674 1/20 0.34
ABL1 P00519 1/20 0.34
NTRK1 P04629 1/20 0.34
CSF1R P07333 1/20 0.34
RET P07949 1/20 0.34
IGF1R P08069 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17897161 0.72 TNF (0.37) HTR2AADRA2AADRA2BHTR2CCYP2A6
SCHEMBL29657656 0.70 TNF (0.36) HTR2AADRA2AADRA2BHTR2CCYP2A6
SCHEMBL30804611 0.69 CA12 (0.55) CA12CA9CYP2A6CA1CA3
SCHEMBL31628328 0.69 MEN1 (0.42) HTR2ACHEK1GSK3BLIMK1DYRK1A
SCHEMBL21048284 0.69 PDPK1 (0.50) CA12CA9HTR1ADRD2HTR2A
SCHEMBL29871305 0.67 CA12 (0.57) CA12CA9CYP2A6CA1CA3
Hydrochloric Acid SCHEMBL29859831 0.67 PDPK1 (0.48) CA12CA9HTR1ADRD2HTR2A
SCHEMBL237720 0.67 CA12 (0.57) CA12CA9CYP2A6CA1CA3
SCHEMBL31484904 0.67 KDM1A (0.36) CYP2A6
SCHEMBL2498909 0.66 KDM4E (0.45) HTR2ACHEK1GSK3BLIMK1DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117616032-A Rare earth complex 东曹株式会社 2024-02-27 CN disclosed