SCHEMBL237720

SCHEMBL237720

O=c1ccc2ccc3ccccc3c2[nH]1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.57
CA9 Q16790 4/20 0.57
CA1 P00915 1/20 0.54
CA3 P07451 1/20 0.54
CA4 P22748 1/20 0.54
CA6 P23280 1/20 0.54
CA5A P35218 1/20 0.54
CA7 P43166 1/20 0.54
CA13 Q8N1Q1 1/20 0.54
CA14 Q9ULX7 1/20 0.54
CA5B Q9Y2D0 1/20 0.54
MCL1 Q07820 1/20 0.52
ALDH1A1 P00352 4/20 0.50
HPGD P15428 2/20 0.50
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 1/20 0.50
USP2 O75604 1/20 0.50
KMT2A Q03164 1/20 0.50
KDM4E B2RXH2 2/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29871305 1.00 CA12 (0.57) CA12CA9CA1CA3CA4
Hydrochloric Acid SCHEMBL31179088 0.98 CA12 (0.55) CA12CA9CA1CA3CA4
SCHEMBL30804611 0.98 CA12 (0.55) CA12CA9CA1CA3CA4
Azetidine SCHEMBL29152261 0.91 CA12 (0.53) CA12CA9CA1CA3CA4
SCHEMBL10749595 0.88 CA12 (0.53) CA12CA9CA1CA3CA4
Pyridine SCHEMBL29180748 0.88 CA12 (0.46) CA12CA9CA1CA3CA4
SCHEMBL10614829 0.83 PDE3B (0.46) CA12CA9CA1CA3CA4
SCHEMBL2116388 0.83 CA12 (0.53) CA12CA9CA1CA3CA4
SCHEMBL9524505 0.80 CA12 (0.56) CA12CA9CA1CA3CA4
SCHEMBL4232096 0.78 CA12 (0.41) CA12CA9CA1CA3CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12227613-B2 Photo-patternable organic semiconductor (OSC) polymers and methods of formation and applications thereof CORNING INCORPORATED (US) 2025-02-18 US claimed
CN-118680931-A Use of phenylquinolinone and flavonoid derivatives for treating neuropathic pain 杭州百诚医药科技股份有限公司 2024-09-24 CN claimed
EP-4225812-B1 KETOQUINOLONES AS PHOTONITIATORS IGM RESINS ITALIA SRL (IT) 2024-09-18 EP claimed
CN-117800963-A Benzoquinolone-cilnidine compound containing exocyclic methylene and preparation method thereof 合肥工业大学 2024-04-02 CN claimed
CN-117486875-A Benzoquinolone-sibiricin alkaloid compound and application thereof 山东大学 2024-02-02 CN claimed
US-20230331958-A1 KETOQUINOLONES AS PHOTONITIATORS IGM RESINS ITALIA S.R.L. (IT) 2023-10-19 US claimed
EP-4225812-A1 KETOQUINOLONES AS PHOTONITIATORS IGM Resins Italia S.r.l. (IT) 2023-08-16 EP claimed
CN-116438205-A Ketoquinolones as photoinitiators 意大利艾坚蒙树脂有限公司 2023-07-14 CN claimed
EP-3356369-B1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO (JP) 2022-05-04 EP claimed
CN-114380982-A Photopatternable Organic Semiconductor (OSC) polymers, methods of forming the same, and uses thereof 康宁股份有限公司 2022-04-22 CN claimed
US-20220119591-A1 PHOTO-PATTERNABLE ORGANIC SEMICONDUCTOR (OSC) POLYMERS AND METHODS OF FORMATION AND APPLICATIONS THEREOF CORNING INCORPORATED 2022-04-21 US claimed
CN-109111400-B Preparation and application of phenylquinolinone and flavonoid derivatives 杭州百诚医药科技股份有限公司 2020-10-16 CN claimed
US-20180269407-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES IDEMITSU KOSAN CO., LTD. (JP) 2018-09-20 US claimed
WO-2005056826-A1 TRANSCRIPTION-PATTERNED BIOLOGICAL ACTIVITY SCREENING SYSTEM THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2005-06-23 WO claimed
EP-0564193-A1 Heteroannulation process ELI LILLY AND COMPANY (US) 1993-10-06 EP claimed
EP-0230967-B1 BENZAZECINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 1991-10-23 EP claimed
US-20260062412-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY CHUGAI PHARMACEUTICAL CO LTD (JP) 2026-03-05 US disclosed
EP-4647424-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-11-12 EP disclosed
US-4749791-A Benzo[f]quinoline intermediates HOFFMANN-LA ROCHE INC. (US) 1988-06-07 US disclosed
US-4732979-A CEREBRAL INSUFFICIENCY HOFFMANN-LA ROCHE INC. (US) 1988-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062412-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND HAVING MYT1 INHIBITORY ACTIVITY MYT1, NTMT1, MYL6 CA12 1692/4885CA9 1476/4885CA1 1098/4885
US-20180269407-A1 BENZIMIDAZOLO[1,2-A]BENZIMIDAZOLE CARRYING TRIAZINE GROUPS FOR ORGANIC LIGHT EMITTING DIODES ALDH1A2, TRPA1, CDK2 CA12 4585/4885CA9 4301/4885CA1 3891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.