Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29657656 | 0.98 | TNF (0.36) | TNFRIPK1AHRMAPTALDH1A1 | |
| SCHEMBL18897739 | 0.75 | ADRA2A (0.48) | AHRMAPTALDH1A1MEN1NPC1 | |
| SCHEMBL4418496 | 0.72 | TYR (0.32) | ADRA2AADRA2BKDM4ECYP2A6GAA | |
| SCHEMBL4424091 | 0.72 | DYRK1A (0.31) | KDM4ECYP2A6 | |
| SCHEMBL30804604 | 0.72 | CA12 (0.41) | MAPTALDH1A1MEN1MAPK1KMT2A | |
| SCHEMBL4419238 | 0.71 | TNF (0.39) | TNFRIPK1AHRMAPTALDH1A1 | |
| SCHEMBL2498909 | 0.69 | KDM4E (0.45) | MAPTALDH1A1HPGDADRA2AADRA2B | |
| SCHEMBL29352476 | 0.69 | KDM4E (0.45) | MAPTALDH1A1HPGDADRA2AADRA2B | |
| SCHEMBL29591462 | 0.69 | TNF (0.54) | TNFRIPK1AHRMEN1POLB | |
| SCHEMBL1374474 | 0.69 | TNF (0.54) | TNFRIPK1AHRMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250073346-A1 | PHARMACEUTICAL COMBINATIONS | OXFORD BIOTHERAPEUTICS LTD (GB) | 2025-03-06 | — | — | US | claimed |
| CN-119462761-A | Thienoindole self-assembled small molecular compound and preparation method and application thereof | 南京信息职业技术学院 | 2025-02-18 | — | — | CN | claimed |
| CN-119060095-A | Self-assembled monomolecular film hole transport material based on fused thienoindole, and preparation method and application thereof | 淮阴工学院 | 2024-12-03 | — | — | CN | claimed |
| EP-4433170-A1 | PHARMACEUTICAL COMBINATIONS | Oxford BioTherapeutics Ltd (GB) | 2024-09-25 | — | — | EP | claimed |
| US-20240254238-A1 | PHARMACEUTICAL COMBINATION COMPRISING AN ANTI-CD205 ANTIBODY AND AN IMMUNE CHECKPOINT INHIBITOR | OXFORD BIOTHERAPEUTICS LTD. (GB) | 2024-08-01 | — | — | US | claimed |
| EP-4346882-A1 | PHARMACEUTICAL COMBINATION COMPRISING AN ANTI-CD205 ANTIBODY AND AN IMMUNE CHECKPOINT INHIBITOR | Oxford BioTherapeutics Ltd (GB) | 2024-04-10 | — | — | EP | claimed |
| WO-2023089314-A1 | PHARMACEUTICAL COMBINATIONS | OXFORD BIOTHERAPEUTICS LIMITED (GB) | 2023-05-25 | — | — | WO | claimed |
| CN-111393452-B | Asymmetric thieno-indole nuclear small molecule receptor material and preparation method thereof | 湖南科技大学 | 2023-04-07 | — | — | CN | claimed |
| WO-2022248835-A1 | PHARMACEUTICAL COMBINATION COMPRISING AN ANTI-CD205 ANTIBODY AND AN IMMUNE CHECKPOINT INHIBITOR | OXFORD BIOTHERAPEUTICS LTD (GB) | 2022-12-01 | — | — | WO | claimed |
| US-20260069707-A1 | COMBINATION THERAPY WITH ANTIBODY-DRUG CONJUGATES AND HYALURONIDASES | HALOZYME, INC. (US) | 2026-03-12 | — | — | US | disclosed |
| US-20250375530-A1 | ROR1/EGFR BI-SPECIFIC ANTIGEN BINDING MOLECULES | ALMAC DISCOVERY LTD (GB) | 2025-12-11 | — | — | US | disclosed |
| US-20250331107-A1 | ORGANIC FILM AND METHOD FOR PRODUCING SAME | SHIKOKU CHEM (JP) | 2025-10-23 | — | — | US | disclosed |
| US-20250263580-A1 | METAL SURFACE TREATMENT LIQUID | SHIKOKU CHEMICALS CORPORATION (JP) | 2025-08-21 | — | — | US | disclosed |
| EP-4543489-A1 | ROR1/EGFR BI-SPECIFIC ANTIGEN BINDING MOLECULES | Almac Discovery Limited (GB) | 2025-04-30 | — | — | EP | disclosed |
| CN-114361180-A | Semiconductor device and display device including the same | 株式会社半导体能源研究所 | 2022-04-15 | — | — | CN | disclosed |
| US-20220073793-A1 | ADHESIVE COMPOSITION, METHOD FOR PRODUCING SURFACE-TREATED METAL MEMBER, AND METHOD FOR PRODUCING METAL-RESIN COMPOSITE BODY | MEC COMPANY LTD. (JP) | 2022-03-10 | — | — | US | disclosed |
| CN-113026008-B | Composition for forming coating film, method for producing surface-treated metal member, and method for producing metal-resin composite | MEC股份有限公司 | 2022-02-25 | — | — | CN | disclosed |
| CN-114031754-A | Thermally activated delayed fluorescence polymer and application thereof | 南京邮电大学 | 2022-02-11 | — | — | CN | disclosed |
| US-20160197275-A1 | EMITTER HAVING A CONDENSED RING SYSTEM | MERCK PATENT GMBH (DE) | 2016-07-07 | — | — | US | disclosed |
| US-20160197275-A1 | EMITTER HAVING A CONDENSED RING SYSTEM | MERCK PATENT GMBH (DE) | 2016-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260069707-A1 | COMBINATION THERAPY WITH ANTIBODY-DRUG CONJUGATES AND HYALURONIDASES | CD22, CD2, CD44 | TNF 541/4885RIPK1 2804/4885AHR 529/4885 |
| US-20250375530-A1 | ROR1/EGFR BI-SPECIFIC ANTIGEN BINDING MOLECULES | EGFR, ROR1, ERBB2 | TNF 3604/4885RIPK1 2559/4885AHR 606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.