Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26111459 | 1.00 | RORC (0.42) | RORCUSP2SMN1; SMN2USP30SCD5 | |
| SCHEMBL31567039 | 0.92 | USP2 (0.42) | RORCUSP2SMN1; SMN2USP30SCD5 | |
| SCHEMBL21301106 | 0.91 | HPGD (0.40) | RORCUSP2SMN1; SMN2USP30SCD5 | |
| SCHEMBL3247703 | 0.91 | USP2 (0.47) | RORCUSP2SMN1; SMN2TACR1ALOX15 | |
| SCHEMBL26112682 | 0.87 | USP2 (0.41) | RORCUSP2SMN1; SMN2USP30SCD5 | |
| SCHEMBL1949274 | 0.85 | RORC (0.41) | RORCUSP2SMN1; SMN2USP30SCD5 | |
| SCHEMBL10205806 | 0.85 | RORC (0.39) | RORCUSP2SMN1; SMN2USP30SCD5 | |
| SCHEMBL5749975 | 0.80 | USP2 (0.46) | USP2SMN1; SMN2TACR1HDAC2ALOX15 | |
| SCHEMBL31566645 | 0.79 | USP2 (0.40) | RORCUSP2SMN1; SMN2USP30SCD5 | |
| SCHEMBL25286793 | 0.79 | USP2 (0.47) | USP2SMN1; SMN2USP30SCD5CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587021-A1 | TREATING PKU WITH CORRECTORS OF MAMMALIAN SLC6A19 FUNCTION | Jnana Therapeutics Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-120076805-A | Treatment of PKU with a mammalian SLC6A19 functional modifier | 杰那医疗公司 | 2025-05-30 | — | — | CN | disclosed |
| WO-2024059005-A1 | TREATING PKU WITH CORRECTORS OF MAMMALIAN SLC6A19 FUNCTION | JNANA THERAPEUTICS INC. (US) | 2024-03-21 | — | — | WO | disclosed |