Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749975 | 0.91 | USP2 (0.46) | USP2SMN1; SMN2HDAC2HDAC1TACR1 | |
| SCHEMBL30805342 | 0.87 | RORC (0.42) | USP2SMN1; SMN2RORCHDAC2CYP11B2 | |
| SCHEMBL26111459 | 0.87 | RORC (0.42) | USP2SMN1; SMN2RORCHDAC2CYP11B2 | |
| SCHEMBL31567039 | 0.82 | USP2 (0.42) | USP2SMN1; SMN2RORCHDAC2CYP11B2 | |
| SCHEMBL3247703 | 0.80 | USP2 (0.47) | USP2SMN1; SMN2RORCTACR1HPGD | |
| SCHEMBL30693981 | 0.80 | USP2 (0.42) | USP2SMN1; SMN2HDAC2HDAC1TACR1 | |
| SCHEMBL29626659 | 0.79 | DGAT1 (0.37) | EPHX2 | |
| SCHEMBL29985644 | 0.79 | USP2 (0.42) | USP2SMN1; SMN2RORCHDAC2CYP11B2 | |
| SCHEMBL27190515 | 0.79 | USP2 (0.42) | USP2SMN1; SMN2RORCHDAC2CYP11B2 | |
| SCHEMBL21301106 | 0.78 | HPGD (0.40) | USP2SMN1; SMN2RORCUSP30SCD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4504719-A1 | EGFR INHIBITORS | Blueprint Medicines Corporation (US) | 2025-02-12 | — | — | EP | disclosed |
| CN-119325471-A | EGFR inhibitors | 缆图药品公司 | 2025-01-17 | — | — | CN | disclosed |
| WO-2023196283-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2023196283-A1 | EGFR INHIBITORS | BLUEPRINT MEDICINES CORPORATION (US) | 2023-10-12 | — | — | WO | disclosed |