Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 12/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 10/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30805801 | 0.87 | KDM4E (0.36) | KDM4EMEN1ALDH1A1LMNAHTT | |
| SCHEMBL25224949 | 0.86 | RORC (0.36) | KDM4EMEN1ALDH1A1LMNAHTT | |
| SCHEMBL30414817 | 0.79 | MEN1 (0.37) | KDM4EMEN1ALDH1A1LMNAHTT | |
| SCHEMBL25220703 | 0.79 | MEN1 (0.37) | KDM4EMEN1ALDH1A1LMNAHTT | |
| SCHEMBL30805808 | 0.78 | GSTP1 (0.38) | MEN1ALDH1A1LMNAKMT2ABCL2 | |
| SCHEMBL29482112 | 0.76 | NPY5R (0.38) | KDM4EMEN1ALDH1A1LMNAHTT | |
| SCHEMBL30447634 | 0.75 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL29748008 | 0.75 | CNR2 (0.39) | KDM4EMEN1ALDH1A1LMNAHTT | |
| SCHEMBL31019217 | 0.74 | KCNH2 (0.39) | ALDH1A1BCL2BCL2L1VCP | |
| SCHEMBL30311297 | 0.73 | PRKCQ (0.36) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118215661-A | Compounds as BCL-2 inhibitors | 重庆复创医药研究有限公司 | 2024-06-18 | — | — | CN | disclosed |
| WO-2024032776-A1 | COMPOUNDS AS BCL-2 INHIBITORS | FOCHON BIOSCIENCES, LTD. (CN) | 2024-02-15 | — | — | WO | disclosed |