Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 2/20 | 0.42 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | RYR2 | Q92736 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6618255 | 1.00 | CD44 (0.42) | CD44PNMTMAOBASIC3RYR2 | |
| SCHEMBL2845218 | 0.89 | CD44 (0.39) | CD44PNMTMAOBASIC3RYR2 | |
| SCHEMBL2161648 | 0.82 | PNMT (0.34) | CD44PNMTMAOBASIC3HTR2C | |
| SCHEMBL2400223 | 0.81 | — | — | |
| SCHEMBL288016 | 0.77 | — | — | |
| SCHEMBL29376210 | 0.77 | — | — | |
| SCHEMBL2843730 | 0.74 | CRBN (0.38) | ASIC3HTR2CSMN1; SMN2HTR2AHTR2B | |
| SCHEMBL38950 | 0.73 | NNMT (0.44) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| SCHEMBL29416448 | 0.73 | NNMT (0.44) | HTR2CHTR2AHTR2BADRA2AADRA2B | |
| SCHEMBL12822 | 0.72 | PNMT (0.52) | CD44PNMTMAOBASIC3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948036-A | Compounds for the treatment of huntington's disease | 渤健马萨诸塞州股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| EP-4562018-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | Biogen MA Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-119948036-A | Compounds for the treatment of huntington's disease | 渤健马萨诸塞州股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024026061-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | BIOGEN MA INC. (US) | 2024-02-01 | — | — | WO | disclosed |