Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775841 | 0.78 | CHRNA1 (0.32) | — | |
| SCHEMBL2777061 | 0.78 | OPRM1 (0.30) | OPRL1 | |
| SCHEMBL2776080 | 0.78 | HTR2C (0.33) | — | |
| SCHEMBL2773979 | 0.74 | — | — | |
| SCHEMBL2777119 | 0.74 | CHRNA1 (0.31) | — | |
| SCHEMBL2775826 | 0.71 | NPSR1 (0.36) | — | |
| SCHEMBL2777591 | 0.69 | CYP11B1 (0.30) | — | |
| SCHEMBL2775705 | 0.69 | GRIA1 (0.33) | — | |
| SCHEMBL2774471 | 0.66 | GRIA1 (0.42) | — | |
| SCHEMBL2777523 | 0.65 | GRIA1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2147915-B1 | New cycloalkylated benzothiadiazine derivatives, method of preparing same and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2010-09-15 | — | — | EP | disclosed |
| EP-2147915-A1 | New cycloalkylated benzothiadiazine derivatives, method of preparing same and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2010-01-27 | — | — | EP | disclosed |